NURS 6501 – Advanced Pathophysiology Discussion Essay Assignments and Question and Answer Quizzes

Advanced practice nurses need a comprehensive understanding of pathophysiological disease processes throughout the lifespan. This course delves into the biophysiological processes, deviations from these processes, and a thorough exploration of scientific concepts related to the biology of disease. Students in advanced practice nursing acquire knowledge about the normal functioning of organ systems and their interrelation to maintain homeostasis.

By delving into the intricacies of pathophysiological disease processes, students gain insights essential for formulating effective treatment plans for patients across different life stages. The curriculum covers various topics, including immunity, inflammation, cancer genetics, and cardiovascular disease. Additionally, students examine a spectrum of disease processes such as hematologic, renal, neurologic, gastrointestinal, and reproductive disorders.

*Note: Students have the option to take this course as a non-degree course, allowing enrollment without being part of a specific program.

NURS 6501 – Advanced Pathophysiology Discussion Essay Assignments and Question and Answer Quizzes

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Module 1: Foundational Concepts of Cellular Pathophysiology

This course is structured into eight (8) distinct modules, each addressing a comprehensive topic. Each module encompasses specific subtopics for focused learning during the week. As you progress through the course, you will consolidate your knowledge through various activities such as Knowledge Checks and Case Study Assignments.

Module 1: Foundational Concepts of Cellular Pathophysiology

spans over 2 weeks, covering Weeks 1 and 2 of the course. During this module, you will delve into the fundamental concepts of cellular processes, exploring the deviations leading to various diseases. The examination will extend to the genetic environment and its influence on disease development. Additionally, you will evaluate the impact of patient characteristics, including racial and ethnic variables, on physiological functioning.

Tasks and Timeline:

  • Review Learning Resources from Days 1–7, Weeks 1 and 2
  • Discussion: “Alterations in Cellular Processes” – Post by Day 3 of Week 1 and respond to colleagues by Day 6 of Week 1
  • Module 1 Assignment: “Case Study Analysis” – Work on it throughout the module, due on Day 7 of Week 2

Week 1 Overview: Cellular Processes and the Genetic Environment

This week emphasizes understanding cells as the “building blocks” of life, emphasizing healthy cellular activity and its impact on good health. The focus is on cellular processes subject to alterations leading to diseases, evaluating the genetic environment’s role and its impact on disease.

Week 1 Learning Objectives:

  • Evaluate cellular processes and alterations within cellular processes.
  • Evaluate the impact of the genetic environment on disease.

Week 1 Learning Resources:

  • Required Readings (click to expand/reduce)
  • Required Media (click to expand/reduce)

Week 1 Discussion: Alterations in Cellular Processes

Understanding diseases at the cellular level is crucial. Diseases, such as cystic fibrosis and Parkinson’s Disease, often arise due to alterations preventing normal cellular functioning. For this Discussion, analyze a provided case study, explaining the suggested disease, symptoms, involved cells, potential alterations, and impacts. Engage in thoughtful discussions with peers, understanding different perspectives on the presented scenario.

What’s Coming Up in Week 2? Next week, the focus shifts to alterations in the immune system and resultant disease processes. Consideration will be given to patient characteristics, including racial and ethnic variables, that might impact altered physiology.

Note: Ensure timely submission and follow the provided rubric for grading criteria.

NURS 6501 – Advanced Pathophysiology Discussion Essay Assignments and Question and Answer Quizzes

Discussion Evaluation CriteriaExcellent (45-50%)Good (40-44%)Fair (35-39%)Poor (0-34%)
Main PostingAnswers all parts of the Discussion question(s) with reflective critical analysis and synthesis of knowledge gained from the course readings. Supported by at least three current, credible sources. Written clearly and concisely with no grammatical or spelling errors and fully adheres to current APA manual writing rules and style.Responds to the Discussion question(s) with reflective critical analysis and synthesis. At least 75% of the post has exceptional depth and breadth. Supported by at least three credible sources. Written clearly and concisely with one or no grammatical or spelling errors and fully adheres to current APA manual writing rules and style.Responds to some of the Discussion question(s). One or two criteria are not addressed or are superficially addressed. Is somewhat lacking reflection and critical analysis and synthesis. Somewhat represents knowledge gained from the course readings. Post is cited with two credible sources. Written somewhat concisely; may contain more than two spelling or grammatical errors. Contains some APA formatting errors.Does not respond adequately to the Discussion question(s). Lacks depth or superficially addresses criteria. Lacks reflection and critical analysis and synthesis. Does not represent knowledge gained from the course readings. Contains only one or no credible sources. Not written clearly or concisely. Contains more than two spelling or grammatical errors. Does not adhere to current APA manual writing rules and style.
Main Post: TimelinessPosts the main post by Day 3.N/AN/ADoes not post the main post by Day 3.
First ResponseResponse exhibits synthesis, critical thinking, and application to practice settings. Provides clear, concise opinions supported by at least two scholarly sources. Demonstrates synthesis and understanding of Learning Objectives. Communication is professional and respectful to colleagues. Responses to faculty questions are fully answered, if posed. Response is effectively written in standard, edited English.Response exhibits critical thinking and application to practice settings. Communication is professional and respectful to colleagues. Responses to faculty questions are answered, if posed. Provides clear, concise opinions supported by two or more credible sources. Response is effectively written in standard, edited English.Response is on topic and may have some depth. Responses posted in the Discussion may lack effective professional communication. Responses to faculty questions are somewhat answered, if posed. Response may lack clear, concise opinions and ideas, and a few or no credible sources are cited.Response may not be on topic and lacks depth. Responses posted in the Discussion lack effective professional communication. Responses to faculty questions are missing. No credible sources are cited.
Second ResponseResponse exhibits synthesis, critical thinking, and application to practice settings. Provides clear, concise opinions supported by at least two scholarly sources. Demonstrates synthesis and understanding of Learning Objectives. Communication is professional and respectful to colleagues. Responses to faculty questions are fully answered, if posed. Response is effectively written in standard, edited English.Response exhibits critical thinking and application to practice settings. Communication is professional and respectful to colleagues. Responses to faculty questions are answered, if posed. Provides clear, concise opinions supported by two or more credible sources. Response is effectively written in standard, edited English.Response is on topic and may have some depth. Responses posted in the Discussion may lack effective professional communication. Responses to faculty questions are somewhat answered, if posed. Response may lack clear, concise opinions and ideas, and a few or no credible sources are cited.Response may not be on topic and lacks depth. Responses posted in the Discussion lack effective professional communication. Responses to faculty questions are missing. No credible sources are cited.
ParticipationMeets requirements for participation by posting on 3 different days.N/AN/ADoes not meet requirements for participation by posting on 3 different days.
Total Points: 100

Week 2: Altered Physiology

As pivotal figures in the healthcare realm, Advanced Practice Registered Nurses (APRNs) must not only showcase support and compassion but also expertise to enlighten patients about their diagnoses and treatment plans. Beyond grasping the intricacies of diseases and sciences like cellular pathophysiology, APRNs need to become authorities on their patients, comprehending their medical histories, pertinent characteristics, and other variables influencing diagnoses and treatments.

This week delves into the examination of alterations in the immune system and the resulting disease processes. It also scrutinizes patient characteristics, including racial and ethnic variables, and their impact on modified physiology.

Learning Objectives

Students will:

  1. Evaluate cellular processes and alterations within cellular processes.
  2. Analyze alterations in the immune system that result in disease processes.
  3. Identify racial/ethnic variables that may impact physiological functioning.
  4. Evaluate the impact of patient characteristics on disorders and altered physiology.

NURS 6501 – Advanced Pathophysiology Discussion Essay Assignments and Question and Answer Quizzes

Required Readings

  • McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.
    • Chapter 1: Cellular Biology; Summary Review
    • Chapter 2: Altered Cellular and Tissue Biology: Environmental Agents(pp. 46-61; begin again with Manifestations of Cellular Injury pp. 83-97); Summary Review
    • Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids, and Bases,
    • Chapter 4: Genes and Genetic Diseases (stop at Elements of formal genetics); Summary Review
    • Chapter 5: Genes, Environment-Lifestyle, and Common Diseases (stop at Genetics of common diseases); Summary Review
    • Chapter 7: Innate Immunity: Inflammation and Wound Healing
    • Chapter 8: Adaptive Immunity (stop at Generation of clonal diversity); Summary Review
    • Chapter 9: Alterations in Immunity and Inflammation (stop at Deficiencies in immunity); Summary Review
    • Chapter 10: Infection (stop at Infectious parasites and protozoans); (start at HIV); Summary Review
    • Chapter 11: Stress and Disease (stop at Stress, illness & coping); Summary Review
    • Chapter 12: Cancer Biology (stop at Resistance to destruction); Summary Review
    • Chapter 13: Cancer Epidemiology (stop at Environmental-Lifestyle factors); Summary Review (Note: You previously read these chapters in Week 1 and are encouraged to review once again for this week.)
  • Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactions. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from here

Required Media

Module 1 Assignment: Case Study Analysis

An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. However, some diseases can be complex, involving a variety of factors and circumstances impacting their emergence and severity.

Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables can all play a crucial role.

Photo Credit: Getty Images/Hero Images

In this Assignment, you will examine a case study and analyze the symptoms presented. Identify cell, gene, and/or process elements that may be factors in the diagnosis, and explain the implications for patient.